--- title: 3 Potential Side-effects of D-Mannose For UTI Prevention description: There are many d-mannose UTI prevention products on the market, but the FDA does not regulate d-mannose UTI products because they are classified as food supplements. Here are the side effects of d-mannose you should be aware of. Most of the time these side effects are minimal or nonexistent, but people with conditions such as irritable bowel syndrome (IBS) are more likely to experience them. image: https://www.dmanna.com/hubfs/joe-roberts-255308-unsplash%20%281%29.jpg --- [Subscribe + **Save 20%**](https://shop.dmanna.com/collections/dmannose-products) + [![manna (3).png](https://www.dmanna.com/hs-fs/hubfs/manna%20(3).png?width=165&name=manna%20(3).png "manna (3).png")](https://www.dmanna.com/) - [Shop](https://shop.dmanna.com/collections/dmannose-products) - About - [UTI Statistics + Facts](https://www.dmanna.com/urinary-tract-infections-statistics-and-facts) - [Why Dmanna](https://www.dmanna.com/why-us) - [FAQ](https://www.dmanna.com/faq) - [Blog](https://www.dmanna.com/dailydose) - [Log In](https://shop.dmanna.com/account/login) - [Log In](https://shop.dmanna.com/account/login) # [DailyDose Blog](https://www.dmanna.com/dailydose) ### Posts by Tag - [Learning About UTIs (18)](https://www.dmanna.com/dailydose/tag/learning-about-utis) - [UTI Prevention Tips (11)](https://www.dmanna.com/dailydose/tag/uti-prevention-tips) - [Medical Research (7)](https://www.dmanna.com/dailydose/tag/medical-research) ## 3 Potential Side-effects of D-Mannose For UTI Prevention by [Hayley Swinson](https://www.dmanna.com/dailydose/author/hayley-swinson) on Oct 5, 2018 ![3 Potential Side-effects of D-Mannose For UTI Prevention](https://www.dmanna.com/hs-fs/hubfs/joe-roberts-255308-unsplash%20(1).jpg?width=600&name=joe-roberts-255308-unsplash%20(1).jpg)  **Not All D-Mannose Is Created Equal** There are many d-mannose [UTI prevention](https://www.dmanna.com/why-us) products on the market, but the U.S. Food and Drug Administration does not regulate d-mannose [UTI products](https://shop.dmanna.com/products/subscription-uti-prevention) because they are classified as food supplements. ### **Be Cautious! Make Sure You…** 1. Check the ingredients list before you buy. Some [d-mannose](https://www.dmanna.com/faq) UTI products use additives. 2. If you have food allergies, be sure to inquire about the product’s origins. The two most common sources for d-mannose are corn and birchwood. If you are sensitive to corn, be cautious.  #### SEE ALSO: [How Do You Know If You Have A UTI?](https://www.dmanna.com/dailydose/how-do-you-know-if-you-have-a-uti) ## **Potential Side Effects Of D-Mannose For UTI Prevention** **1) Cramping, Bloating, And Diarrhea** *Note: Because most [research on d-mannose](https://www.dmanna.com/urinary-tract-infections-statistics-and-facts) for UTI prevention records **no side-effects**, we are reporting these from individual customer reviews from product sites across the* *web.* Most of the time these side effects are minimal or nonexistent, but people with conditions such as irritable bowel syndrome (IBS) are more likely to experience them. **Talk To Your Doctor Before Taking D-Mannose If You Have Serious Preexisting Conditions** People with small intestinal bacterial overgrowth (SIBO) are significantly more likely to experience serious side effects like debilitating cramps, nausea, and abdominal swelling from taking d-mannose.1 People who have genetic disorders such as MPI-CDG and PMM2-CDG that make it difficult for their bodies to process and digest sugars might suffer complications similar to those seen in diabetics.2 *If you have any of the above disorders, it’s important to talk to a specialist before you start taking d-mannose.* ![3 Potential Side-effects of D-Mannose For UTI Prevention](https://www.dmanna.com/hs-fs/hubfs/becca-tapert-391587-unsplash.jpg?width=600&name=becca-tapert-391587-unsplash.jpg)   [![Want More Info? Download The Ultimate UTI Guide](https://no-cache.hubspot.com/cta/default/4024045/8eff8c89-15fc-4334-88ac-b16267485caa.png)](https://cta-redirect.hubspot.com/cta/redirect/4024045/8eff8c89-15fc-4334-88ac-b16267485caa)   **How to Mitigate Cramping, Bloating, and Diarrhea** If you do experience these symptoms, try changing your dosage. Many d-mannose products come in bulk rather than measured out in daily doses, and there is often confusing, contradictory information about how much you should take and how often. You might also want to try a different brand of [d-mannose](https://www.dmanna.com/why-us). Compare and contrast reviews for each UTI prevention product, and make sure you research the company and their manufacturing processes.  #### SEE ALSO: [Are You At Risk For Chronic UTIs?](https://www.dmanna.com/dailydose/are-you-at-risk-for-chronic-utis) **2) Ineffectiveness Due To High Or Low Urine pH Levels ** Some studies suggest that d-mannose is most effective for [UTI prevention](https://www.dmanna.com/dailydose/why-d-mannose-is-best-for-uti-prevention) when your urine has a neutral pH, that is, below 8 and above 4.5.3 If d-mannose is not preventing your urinary tract infections, grab some pH strips from your local drugstore to find out the pH levels of your urine. If your pH is above 8 or below 4.5, consider taking d-mannose in conjunction with a product to change the pH of your urine to a more neutral number. Ask your doctor for product recommendations. If you do have a high or low urine pH, you may be more at risk for developing kidney stones or other conditions. Talk to your doctor if you think this may be you.  #### SEE ALSO: [Sepsis, Death, And Antibiotic Resistant Superbugs: The Consequences Of Underestimating The Seriousness Of UTIs](https://www.dmanna.com/dailydose/sepsis-death-and-antibiotic-resistant-superbugs-the-consequences-of-underestimating-the-seriousness-of-utis) **Dmanna: High-Quality D-Mannose With No Additives** Dmanna is pure d-mannose. Dmanna users end up taking FEWER antibiotics by including Dmanna in their daily health routines with its convenient, pre-measured packets to kill UTIs before they develop. No measuring or guesswork involved! Want to try the [Dmanna for UTI prevention? Click here to find out how](https://www.dmanna.com/)!  [![Dmanna. Your #1 daily UTI prevention product](https://no-cache.hubspot.com/cta/default/4024045/be6695fe-2d40-4161-8872-d91e2ee6e630.png)](https://cta-redirect.hubspot.com/cta/redirect/4024045/be6695fe-2d40-4161-8872-d91e2ee6e630)   1. [Exercise Caution when Using D-Mannose for a Urinary Tract Infection if You Have SIBO](http://www.holistichelp.net/blog/exercise-caution-using-d-mannose-for-uti-if-have-sibo/) 2. [Mannose metabolism: More than meets the eye](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252654/) 3. [Oral D-mannose in recurrent urinary tract infections in women: a pilot study](http://journals.sagepub.com/doi/pdf/10.1177/2051415813518332) 4. [Nothing to Sneeze at: the Allergenicity of GMOs](http://sitn.hms.harvard.edu/flash/2015/allergies-and-gmos/)     ![dmanna.png](https://www.dmanna.com/hs-fs/hubfs/Blog_Post_Page_Files/dmanna.png?width=355&name=dmanna.png "dmanna.png") ![Pineapple](https://www.dmanna.com/hs-fs/hubfs/Product%20Images/Copy%20of%200F3A3082-min.png?width=320&name=Copy%20of%200F3A3082-min.png "Pineapple") [![Learn More](https://no-cache.hubspot.com/cta/default/4024045/d433d88d-ab69-4ffc-b571-a6b873226520.png)](https://cta-redirect.hubspot.com/cta/redirect/4024045/d433d88d-ab69-4ffc-b571-a6b873226520) ### Subscribe to Blog ###### Share on [![Share on Facebook](https://static.hubspot.com/final/img/common/icons/social/facebook-24x24.png)](http://www.facebook.com/share.php?u=https%3A%2F%2Fwww.dmanna.com%2Fdailydose%2F3-potential-side-effects-of-d-mannose-for-uti-prevention%3Futm_medium%3Dsocial%26utm_source%3Dfacebook) [![Share on Twitter](https://static.hubspot.com/final/img/common/icons/social/twitter-24x24.png)](https://twitter.com/intent/tweet?original_referer=https%3A%2F%2Fwww.dmanna.com%2Fdailydose%2F3-potential-side-effects-of-d-mannose-for-uti-prevention%3Futm_medium%3Dsocial%26utm_source%3Dtwitter&url=https%3A%2F%2Fwww.dmanna.com%2Fdailydose%2F3-potential-side-effects-of-d-mannose-for-uti-prevention%3Futm_medium%3Dsocial%26utm_source%3Dtwitter&source=tweetbutton&text=3%20Potential%20Side-effects%20of%20D-Mannose%20For%20UTI%20Prevention) [![Share on Pinterest](https://static.hubspot.com/final/img/common/icons/social/pinterest-24x24.png)](http://pinterest.com/pin/create/button/?url=https%3A%2F%2Fwww.dmanna.com%2Fdailydose%2F3-potential-side-effects-of-d-mannose-for-uti-prevention%3Futm_medium%3Dsocial%26utm_source%3Dpinterest&media=) [![Share on Email](https://static.hubspot.com/final/img/common/icons/social/email-24x24.png)](mailto:?subject=Check%20out%20https%3A%2F%2Fwww.dmanna.com%2Fdailydose%2F3-potential-side-effects-of-d-mannose-for-uti-prevention%3Futm_medium%3Dsocial%26utm_source%3Demail%20&body=Check%20out%20https%3A%2F%2Fwww.dmanna.com%2Fdailydose%2F3-potential-side-effects-of-d-mannose-for-uti-prevention%3Futm_medium%3Dsocial%26utm_source%3Demail) ## Hot Topics [![Dmanna Blog Featured Image.png](https://www.dmanna.com/hs-fs/hubfs/Dmanna%20Blog%20Featured%20Image.png?width=320&name=Dmanna%20Blog%20Featured%20Image.png "Dmanna Blog Featured Image.png")](https://www.dmanna.com/dailydose/what-everyone-with-recurring-utis-needs-to-know) ### [What Everyone With Recurring UTIs Needs To Know](https://www.dmanna.com/dailydose/what-everyone-with-recurring-utis-needs-to-know) April 12th, 2018 by Dmanna [![Can You Only Get UTIs From Sexual Activity?](https://www.dmanna.com/hs-fs/hubfs/Dmanna%20Blog%20Featured%20Image%20(1).png?width=320&name=Dmanna%20Blog%20Featured%20Image%20(1).png "Can You Only Get UTIs From Sexual Activity?")](https://www.dmanna.com/dailydose/can-you-only-get-utis-from-sexual-activity) ### [Can You Only Get UTIs From Sexual Activity?](https://www.dmanna.com/dailydose/can-you-only-get-utis-from-sexual-activity) April 12th, 2018 by Dmanna [![Chugging Cranberry Juice](https://www.dmanna.com/hs-fs/hubfs/Blog%20Images%20and%20GIFs/asdrubal-luna-485688-unsplash-606160-edited.jpg?width=320&name=asdrubal-luna-485688-unsplash-606160-edited.jpg "Chugging Cranberry Juice")](https://www.dmanna.com/dailydose/why-you-shouldnt-chug-cranberry-juice-when-you-have-a-urinary-tract-infection-uti) ### [Why You Shouldn't Chug Cranberry Juice When You Have A UTI](https://www.dmanna.com/dailydose/why-you-shouldnt-chug-cranberry-juice-when-you-have-a-urinary-tract-infection-uti) April 10th, 2018 by Dmanna [![hot_topic_4.jpg](https://www.dmanna.com/hs-fs/hubfs/Dmanna_Blog_Page_Files/hot_topic_4.jpg?width=401&name=hot_topic_4.jpg "hot_topic_4.jpg")](https://www.dmanna.com/dailydose/are-you-at-risk-for-chronic-utis) ### [Are You At Risk For Chronic UTIs?](https://www.dmanna.com/dailydose/are-you-at-risk-for-chronic-utis) April 16th, 2018 by Dmanna ## Stay informed. 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